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INVESTIGATION OF BONE MINERALIZATION IN PATIENTS WITH CORONARY HEART DISEASE COMPLICATED BY CHRONIC HEART FAILURE,

I Krynytska1, M Marushchak1, T Zaets1

  • 1I. Horbachevsky Ternopil State Medical University, Ukraine.

Georgian Medical News
|July 21, 2017
PubMed

Insights

Patients with coronary heart disease and chronic heart failure show significant bone loss. Nearly half experienced osteopenia or osteoporosis, indicating a link between heart conditions and bone health.

Area of Science:

  • Cardiology
  • Endocrinology
  • Orthopedics

Background:

  • Cardiovascular diseases (CVD) are linked to increased fracture risk due to bone loss.
  • Low bone mass is associated with higher mortality from cardiovascular events.
  • The relationship between coronary heart disease (CHD) and bone health requires further investigation.

Purpose of the Study:

  • To assess bone mineralization in men with coronary heart disease (CHD) complicated by Stage II-A chronic heart failure.
  • To identify the prevalence and stages of bone loss in this patient cohort.

Main Methods:

  • Dual-energy X-ray absorptiometry (DXA) was used to measure bone mineral density (BMD) in the lumbar spine.
  • The study included 33 male patients diagnosed with CHD and Stage II-A chronic heart failure.

Main Results:

  • 49.2% of patients exhibited structural and functional bone tissue changes in the lumbar spine.
  • Prevalence included Stage I osteopenia (44.6%), Stage II osteopenia (27.7%), Stage III osteopenia (10.8%), and osteoporosis (16.9%).
  • A decreasing trend in BMD was observed in L1 across osteopenia stages, with uniform decrease in osteoporosis.

Conclusions:

  • Coronary heart disease complicated by Stage II-A chronic heart failure is associated with significant bone demineralization.
  • Osteopenia and osteoporosis are prevalent in this patient group, highlighting a critical comorbidity.
  • Further research is warranted to explore therapeutic strategies for bone health in cardiovascular patients.

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