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Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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What is the Immune System?01:38

What is the Immune System?

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Overview
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Related Experiment Video

Updated: Feb 14, 2026

DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
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Immunization Coverage in Children with Inflammatory Bowel Disease.

K Kowalska-Duplaga1, M Baranowska-Nowak2, M Nescioruk2

  • 1Department of Pediatrics, Gastroenterology and Nutrition, Jagiellonian University Medical College, Cracow, Poland.

Advances in Experimental Medicine and Biology
|February 12, 2018
PubMed
Summary

Polish children with inflammatory bowel diseases (IBD) have a poor vaccination status. Vaccinations are crucial for preventing infections in these vulnerable children.

Keywords:
Crohn’s diseaseImmunizationImmunosuppressive treatmentInflammatory bowel diseaseUlcerative colitisVaccination

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Area of Science:

  • Pediatrics
  • Immunology
  • Gastroenterology

Background:

  • Patients with inflammatory bowel diseases (IBD) face heightened infection risks, often exacerbated by immunosuppressive therapies.
  • Infections can trigger or worsen IBD flares, underscoring the need for preventative measures.
  • Vaccination is a primary strategy for mitigating infection risks in immunocompromised populations.

Purpose of the Study:

  • To assess the vaccination status of children diagnosed with IBD in Poland.
  • To compare the immunization coverage between IBD patients and healthy controls.

Main Methods:

  • A retrospective review of immunization records for children with IBD and a control group of healthy children.
  • Collection of demographic data, IBD history, and treatment information.
  • Statistical analysis to determine vaccination coverage and associated factors.

Main Results:

  • None of the 267 enrolled children (214 with IBD, 53 controls) had completed the recommended childhood immunization schedule.
  • Children with IBD exhibited significantly lower vaccination rates compared to healthy controls.
  • Controls were over four times more likely to be vaccinated than IBD patients (OR 4.1, 95% CI 2.2-7.9), particularly for insurance-reimbursed vaccines.

Conclusions:

  • The study reveals a concerningly low vaccination coverage among Polish children with IBD.
  • There is a critical need to improve vaccination adherence in pediatric IBD patients to prevent infections and disease complications.