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[Opioids prescription in the vulnerable populations : the children and the elderly. Practical guidelines]
Frédérique Rodieux1, Célia Lloret-Linares1, Valérie Piguet1
1Service de pharmacologie et toxicologie cliniques, Centre multidisciplinaire d'évaluation et de traitement de la douleur, Département d'anesthésiologie, de pharmacologie et des soins intensifs, HUG, 1211 Genève 14.
Abstract:
Pain management in ambulatory care regularly requires the prescription of opioids. These drugs allow adequate analgesia achievement in many patients, but inefficiency and/or intolerable side effects may limit their use. Factors related to physiological particularities, comorbidities and comedication, as well as difficulties related to drug intake and pain assessment, make children and the elderly more vulnerable to variability in opioid response and problems of safety and efficacy profile. The purpose of this article is to remain the specificities of these two populations and to propose recommendations for the good use of opioids for ambulatory care.
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