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Biomedical Perspective of Electrochemical Nanobiosensor
Priti Singh1, Shailendra Kumar Pandey2, Jyoti Singh1
11Department of Biotechnology, Motilal Nehru National Institute of Technology, Allahabad, Uttar Pradesh 211004 India.
Nano-Micro Letters
|November 22, 2018
Summary
Electrochemical biosensors offer sensitive, label-free disease detection at the bedside. This review covers their principles, applications in diagnosing cancer, AIDS, and cardiovascular diseases, and future potential.
Area of Science:
- Biomedical Engineering
- Analytical Chemistry
Background:
- Electrochemical biosensors are valuable for point-of-care diagnostics due to their specificity, sensitivity, and cost-effectiveness.
- They enable rapid, label-free detection of disease biomarkers.
Purpose of the Study:
- To review the working principles of electrochemical biosensors.
- To explore their application in detecting biomarkers for cancer, AIDS, hepatitis, and cardiovascular diseases.
- To discuss recent advances, challenges, and future perspectives in electrochemical biosensor technology.
Main Methods:
- Review of scientific literature on electrochemical biosensor principles and applications.
- Detailed elucidation of recent advances in implantable biosensors and nanomaterial-based electrodes.
- Discussion of electrochemical detection of heavy metal ions.
Main Results:
- Electrochemical biosensors show significant promise for early disease diagnosis.
- Nanomaterials enhance biosensor sensitivity for biomolecule detection.
- The technology is applicable to detecting both disease biomarkers and environmental toxins like heavy metal ions.
Conclusions:
- Electrochemical biosensors are a powerful tool for rapid, sensitive, and cost-effective diagnostics.
- Continued research in nanomaterials and implantable designs will further improve their capabilities.
- Addressing current challenges will unlock the full potential of electrochemical biosensors in healthcare and environmental monitoring.
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