Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

908
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
908
Glaucoma: Overview01:25

Glaucoma: Overview

1.2K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.2K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.1K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evidence and Consensus Based Guidelines for Imaging in Tubercular Choroiditis. Multimodal imaging in Uveitis (MUV) Taskforce: Report 17.

Ophthalmology. Retina·2026
Same author

Anti-Adalimumab Antibodies in Patients with Inflammatory Ocular Diseases: Incidence and Clinical Outcomes.

American journal of ophthalmology·2026
Same author

Evidence and Consensus-Based Guidelines in Vogt-Koyanagi-Harada Disease. Multimodal Imaging in Uveitis (MUV) Taskforce Report 16.

Ophthalmology. Retina·2026
Same author

One-year CALM Outcomes: Data From a Real-world Registry Study of the 0.18-mg Fluocinolone Acetonide Intravitreal Implant for the Treatment of Patients With Non-infectious Uveitis Affecting the Posterior Segment.

Ophthalmic surgery, lasers & imaging retina·2026
Same author

Deconstructing White Dot Syndromes-Multimodal Imaging in Uveitis (MUV) Taskforce: Report 11.

American journal of ophthalmology·2026
Same author

Evidence and Consensus-Based Imaging Guidelines in Cytomegalovirus Retinitis: Multimodal Imaging in Uveitis (MUV) Task Force - Report 15.

Ophthalmology. Retina·2026
Same journal

Role of Adjunctive Intravitreal Therapy in Intraocular Tubercular Granuloma at a Tertiary Uveitis Care Centre - A Retrospective Case Series.

Ocular immunology and inflammation·2026
Same journal

Sex Differences in Uveitis Etiology: A Systematic Review and Meta-Analysis.

Ocular immunology and inflammation·2026
Same journal

Upadacitinib in Refractory Vogt-Koyanagi-Harada Disease: A Case Report.

Ocular immunology and inflammation·2026
Same journal

Choroidal and Retinal Imaging Findings in Childhood-Onset Mevalonate Kinase Deficiency: An OCT-Based Case-Control Study.

Ocular immunology and inflammation·2026
Same journal

Efficacy of infliximab therapy in the treatment of idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome.

Ocular immunology and inflammation·2026
Same journal

Conjunctival Reactive Lymphoid Hyperplasia with Delayed Corneal Immune Infiltrates in the Setting of Systemic Epstein-Barr Virus Infection.

Ocular immunology and inflammation·2026
See all related articles

Related Experiment Video

Updated: Jan 2, 2026

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

14.5K

Visual Acuity Outcome over Time in Non-Infectious Uveitis.

Maxwell Pistilli1,2, Marshall M Joffe3, Sapna S Gangaputra4

  • 1The Scheie Eye Institute, The University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

Ocular Immunology and Inflammation
|December 11, 2019
PubMed
Summary
This summary is machine-generated.

Visual acuity (VA) in noninfectious uveitis patients improved significantly over two years in subspecialty care. This improvement was generally sustained, suggesting VA change is a valuable clinical study outcome.

Keywords:
UveitisVisual acuityinverse probability of censoring weighting

More Related Videos

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

3.1K
The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish
04:56

The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish

Published on: October 9, 2013

21.0K

Related Experiment Videos

Last Updated: Jan 2, 2026

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

14.5K
Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

3.1K
The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish
04:56

The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish

Published on: October 9, 2013

21.0K

Area of Science:

  • Ophthalmology
  • Immunology

Background:

  • Noninfectious uveitis affects vision and requires long-term management.
  • Visual acuity (VA) is a key measure of visual function in uveitis patients.

Purpose of the Study:

  • To evaluate changes in visual acuity (VA) over five years in a large cohort of noninfectious uveitis patients.
  • To compare VA outcomes across different types of noninfectious uveitis (anterior, intermediate, posterior, panuveitis).

Main Methods:

  • Retrospective analysis of data from 5,530 noninfectious uveitis patients.
  • Mean VA calculated using inverse probability of censoring weighting to manage loss to follow-up.
  • Analysis included patients with anterior, intermediate, posterior, or panuveitis.

Main Results:

  • Mean VA was initially worse in panuveitis (20/84) compared to posterior (20/64), intermediate (20/47), and anterior (20/37) uveitis.
  • Over two years, mean VA improved significantly (P < .001) by 0.62 (panuveitis), 0.51 (posterior), 0.37 (intermediate), and 0.26 (anterior) logMAR-equivalent lines.
  • VA improvements were generally sustained, though posterior uveitis showed a trend towards worsening back to initial levels.

Conclusions:

  • Mean visual acuity in eyes with noninfectious uveitis improves under subspecialty care.
  • The observed VA improvement is typically sustained over time.
  • Mean VA change is a more sensitive outcome measure for clinical studies than time-to-loss of VA.