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CCL20 Signaling in the Tumor Microenvironment

Weilong Chen1,2,3, Yuanyuan Qin1,2,3, Suling Liu4,5,6

  • 1Fudan University Shanghai Cancer Center & Institutes of Biomedical Sciences, Shanghai Medical College, Shanghai, China.

Advances in Experimental Medicine and Biology
|February 16, 2020
PubMed
Summary

Chemokine CCL20 (CC-chemokine ligand 20) promotes cancer progression by influencing the tumor microenvironment (TME). Understanding CCL20 signaling is crucial for developing novel cancer therapies.

Keywords:
CCL20CCR6CancerChemokineCytokineDendritic cells (DCs)NF-κBRegulatory T cells (Tregs)T helper 17 cells (Th17 cells)Tumor microenvironment (TME)

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