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Updated: Nov 19, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Published on: July 11, 2013

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[Switching from atopic dermatitis to psoriasis - and back]

Wolf-Henning Boehncke1, Romaine Stalder2, Nicolò Costantino Brembilla2

  • 1Service de dermatologie et vénéréologie, Département des spécialités de médecine, HUG, 1211 Genève 14.

Revue Medicale Suisse
|January 28, 2021
PubMed

Insights

Atopic dermatitis and psoriasis are distinct skin conditions. Therapies targeting one disease can sometimes trigger the other, offering new insights into their pathophysiology and treatment.

Area of Science:

  • Dermatology
  • Immunology
  • Pathophysiology

Background:

  • Atopic dermatitis and psoriasis are clinically and pathogenetically distinct inflammatory skin diseases.
  • Targeted therapies have advanced treatment by inhibiting key pathogenic pathways.

Purpose of the Study:

  • To explore the interplay between atopic dermatitis and psoriasis.
  • To understand how therapies for one condition can influence the other.

Main Methods:

  • Observational analysis of treatment-induced disease onset.
  • Review of clinical and pathogenetic data.

Main Results:

  • Specific therapies for atopic dermatitis or psoriasis can occasionally induce the onset of the other condition.
  • This phenomenon highlights shared or interconnected pathogenic mechanisms.

Conclusions:

  • The cross-induction of atopic dermatitis and psoriasis suggests a more complex relationship than previously understood.
  • These findings have implications for the management and therapeutic strategies for both inflammatory skin diseases.

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