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Neovascular Glaucoma in MELAS syndrome
Saira Khanna1, Bradley T Smith1
1The Retina Institute, 2201 S. Brentwood Blvd, St. Louis, MO, 63144, USA.
American Journal of Ophthalmology Case Reports
|May 6, 2024
Summary
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) can rarely cause neovascular glaucoma, especially in diabetic patients. This case highlights the importance of suspecting MELAS with specific symptoms.
Area of Science:
- Ophthalmology
- Neurology
- Genetics
Background:
- Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) is a rare genetic disorder.
- Ocular complications in MELAS are uncommon, with neovascular glaucoma being particularly rare.
Observation:
- This study details a unique case of a patient diagnosed with MELAS.
- The patient presented with a history of diabetes, hearing loss, and macular dystrophy.
Findings:
- The patient developed neovascular glaucoma, an unusual manifestation of MELAS.
- This ocular complication was observed in conjunction with the patient's other MELAS-related symptoms.
Implications:
- The findings underscore the need to consider MELAS in patients presenting with this specific cluster of symptoms, including ocular issues.
- Early diagnosis and management of MELAS can potentially mitigate severe complications like neovascular glaucoma.
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