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Updated: Jun 22, 2025

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
[Epidemiological signatures and surveillance bias in cancer]
Stefano Tancredi1, Bernadette van der Linden1, Laura Rosella2,3
1Laboratoire de santé des populations (#PopHealthLab), Université de Fribourg, 1700 Fribourg.
Abstract:
Surveillance bias occurs when variations in cancer incidence are the result of changes in screening or diagnostic practices rather than increases in the true occurrence of cancer. This bias is linked to the issue of overdiagnosis and can be apprehended by looking at epidemiological signatures of cancer. We explain the concept of epidemiological signatures using the examples of melanoma and of lung and prostate cancer. Accounting for surveillance bias is particularly important for assessing the true burden of cancer and for accurately communicating cancer information to the population and decision-makers.
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