Related Experiment Video
Updated: May 5, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
[Posterior cruciate ligament rupture : state of the art]
Vasileios Mitrousias1, Philippe Tscholl2, Jacques Menetrey1,2
1Centre de médecine du sport et de l'exercice, Swiss Olympic Medical Center, Hirslanden Clinique La Colline, 1206 Genève.
Abstract:
Posterior cruciate ligament (PCL) ruptures can cause severe knee instability and disability and thus, appropriate management is crucial for the successful restoration of patients' knee function. Rupture of the PCL can occur during sporting activity but more often, as a part of high-energy trauma. The diagnosis can be made using various clinical tests, such as the posterior drawer test or the quadriceps active test. MRI is the gold standard in imaging. PCL injuries can be classified from grade I to grade III, with increasing severity. Treatment can be conservative or surgical and should be personalized based on patients' demographic characteristics, grade of injury, level of instability, associated injuries and activity levels.

