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Updated: Jun 19, 2026

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Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV
Published on: September 14, 2010
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"Chasing Rainbows" Beyond Kaposi Sarcoma's Dermoscopy: A Mini-Review.
Emmanouil Karampinis1,2, Olga Toli3, Georgia Pappa4
1Second Dermatology Department, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Dermatopathology (Basel, Switzerland)
|December 27, 2024
Summary
The dermoscopic rainbow pattern (RP), a multicolored appearance, is typically linked to Kaposi's sarcoma but can also signal other skin conditions. This study reviews factors influencing RP occurrence in diverse lesions.
Area of Science:
- Dermatology
- Optical Physics
- Pathology
Background:
- The dermoscopic rainbow pattern (RP) presents as a multicolored appearance due to light dispersion.
- While highly specific for Kaposi's sarcoma, RP is also observed in other skin entities.
Purpose of the Study:
- To present cases of pigmented basal cell carcinoma and aneurysmatic dermatofibroma with RP.
- To review skin conditions exhibiting RP and identify predisposing factors.
Main Methods:
- Literature review of 33 case reports and studies on lesions with RP.
- Analysis of identified skin conditions and associated predisposing factors.
Main Results:
- RP was identified in diverse lesions including skin cancers, vascular tumors, nevi, and inflammatory dermatoses.
- Lesions with RP were predominantly on extremities.
- Predisposing factors included nodular shape, vascularization, pigmentation, depth, and thickness.
Conclusions:
- The dermoscopic rainbow pattern is not exclusive to Kaposi's sarcoma.
- Lesion characteristics like shape, composition, vascularity, pigmentation, depth, and thickness influence RP development.
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