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Office-Based Lymph Node Biopsy: A Comprehensive Literature Review.
Michael Chaney1, Tyler Anderson1, Saad Shebrain1
1General Surgery, Western Michigan University Homer Stryker M.D. School of Medicine, 1000 Oakland Drive, Kalamazoo, MI 49008, USA.
The Surgical Clinics of North America
|June 28, 2025
Summary
Performing minor lymph node biopsies in an office setting is feasible and beneficial. This approach offers a cost-effective and convenient alternative to in-hospital procedures for patients.
Area of Science:
- Medical procedures
- Oncology
- Diagnostic techniques
Background:
- Increasing healthcare costs necessitate exploring cost-effective medical solutions.
- There is a growing trend towards minimally invasive procedures in medicine.
- Office-based procedures can enhance patient convenience and reduce healthcare burdens.
Purpose of the Study:
- To assess the feasibility of performing lymph node biopsies in an office setting.
- To evaluate the cost-effectiveness and patient convenience of office-based lymph node biopsies.
Main Methods:
- Excisional biopsy of accessible lymph nodes.
- Ultrasound-guided core needle biopsy of lymph nodes.
- Ultrasound-guided aspirational biopsy of lymph nodes.
Main Results:
- Minor lymph node biopsies, including excisional and ultrasound-guided methods, can be successfully performed in an office environment.
- Proper patient selection and preparation are key to successful outcomes.
- Office-based procedures demonstrate cost-effectiveness.
Conclusions:
- Physicians should consider the feasibility of office-based lymph node biopsies.
- This approach offers a practical, cost-effective, and convenient option for patient care.
- Successful implementation relies on careful patient selection and preparation.

