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Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
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Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
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Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
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Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
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[Treatment for smoking cessation : situation in 2025].

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Smoking is declining in Switzerland, but new nicotine products like e-cigarettes are rising, especially among youth. Cytisine shows renewed promise as an effective smoking cessation aid.

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Area of Science:

  • Public Health
  • Pharmacology
  • Addiction Medicine

Context:

  • Rising use of novel nicotine products (electronic cigarettes, snus) among young people in Switzerland.
  • Conventional cigarettes remain the most prevalent nicotine product.
  • Limited approved pharmacotherapies for smoking cessation in Switzerland (nicotine replacement therapy, bupropion).

Purpose:

  • To evaluate the effectiveness and acceptability of cytisine for smoking cessation.
  • To address the gap in smoking cessation options following varenicline withdrawal.

Summary:

  • Cytisine, an older smoking cessation drug, is regaining interest due to its similar mechanism of action to varenicline.
  • Recent studies indicate cytisine is effective and acceptable for individuals seeking to quit smoking.
  • The study highlights cytisine as a viable alternative in the Swiss smoking cessation landscape.

Impact:

  • Potential to expand smoking cessation treatment options in Switzerland.
  • Offers a renewed therapeutic avenue for nicotine addiction management.
  • Supports public health initiatives by providing evidence for an accessible cessation aid.