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Enhancing India's Health Security Efforts Against Mycobacterium Tuberculosis : Gaps and Opportunities
Abhijit Poddar1, Sourik Mukherjee1, S R Rao1
1Abhijit Poddar, PhD, is Chief, Centre for Bio-Policy Research (CBPR), Mahatma Gandhi Medical Advanced Research Institute (MGMARI), Sri Balaji Vidyapeeth (Deemed-to-be-University), Pondicherry, India, and co-founder of Genentech Regulatory Solutions LLP, Hyderabad, India. Sourik Mukherjee, MSc, is a Research Scholar, MGMARI, Sri Balaji Vidyapeeth (Deemed-to-be-University), Pondicherry, India. S. R. Rao, PhD, is Founder and Director, Genentech Regulatory Solutions LLP, Hyderabad, India, and Former Senior Advisor, Department of Biotechnology, Ministry of Science and Technology, Government of India, New Delhi, India.
India faces a significant tuberculosis (TB) burden and aims for elimination by 2025. However, persistent challenges like drug resistance and weak infrastructure necessitate a revised, evidence-based strategy aligned with global goals.
Area of Science:
- Public Health
- Infectious Diseases
- Global Health Security
Background:
- India shoulders a quarter of the global tuberculosis (TB) burden.
- The nation set an ambitious target to eliminate TB by 2025, surpassing the global goal.
- Despite public health initiatives like Pradhan Mantri TB Mukt Bharat Abhiyan, progress is threatened by persistent challenges.
Purpose of the Study:
- To highlight underaddressed health security challenges impacting TB elimination in India.
- To advocate for a revised TB elimination strategy aligned with the global 2030 target.
- To emphasize the need for evidence-based policy and multisectoral coordination.
Main Methods:
- Review of existing TB elimination strategies and their limitations in India.
- Identification of critical health security challenges, including multidrug-resistant TB and weak biosafety.
- Analysis of environmental and social determinants affecting TB control.
Main Results:
- Persistent challenges include data transparency issues, overburdened healthcare systems, and an unrealistic timeline.
- Underaddressed issues include multidrug-resistant TB, weak biosafety, lack of post-treatment monitoring, environmental factors, and inadequate strategies for vulnerable populations.
- Current strategies may not be sufficient to meet the ambitious 2025 elimination goal.
Conclusions:
- A revised approach to TB elimination is crucial for India.
- Key elements for success include evidence-based policy, improved surveillance, workforce support, and multisectoral coordination.
- Environmental and technological interventions are vital for comprehensive TB control and elimination.
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