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Updated: Jun 12, 2026

Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
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Transarterial Therapy for Liver Tumors.

Zuzanna Kobus1, Anita Karimi1, Hooman Yarmohammadi1

  • 1Division of Interventional Radiology, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

Hematology/Oncology Clinics of North America
|June 10, 2026
PubMed
Summary

Transarterial therapies (TATs) offer targeted locoregional treatment for unresectable liver tumors by exploiting the liver

Keywords:
ChemoembolizationHepatic artery embolizationHepatocellular carcinomaLiver metastasisLiver tumorRadioembolizationSecondary liver cancerTransarterial therapy

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Area of Science:

  • Hepatology and Interventional Radiology
  • Oncology
  • Vascular Medicine

Background:

  • Liver tumors, both primary and secondary, pose a significant global health burden.
  • Many cases are diagnosed when curative surgical options are unavailable.
  • Locoregional therapies are crucial for managing unresectable liver malignancies.

Purpose of the Study:

  • To provide a comprehensive review of transarterial therapies (TATs) for liver tumors.
  • To focus on patient selection, procedural techniques, and clinical outcomes.
  • To cover both primary and secondary liver malignancies.

Main Methods:

  • Review of existing literature on transarterial therapies.
  • Analysis of different TAT modalities: embolization, chemoembolization, and radioembolization.
  • Discussion of the liver's dual blood supply in targeted therapy.

Main Results:

  • TATs selectively target tumor tissue while sparing healthy liver parenchyma.
  • Different TATs have distinct mechanisms, technical requirements, and applications.
  • The review synthesizes evidence on the effectiveness of TATs in various liver cancer types.

Conclusions:

  • Transarterial therapies are essential treatment options for unresectable liver tumors.
  • Careful patient selection and understanding procedural principles are key to successful outcomes.
  • TATs represent a vital strategy in the multidisciplinary management of liver malignancies.