Transarterial Therapy for Liver Tumors

Primary and secondary liver tumors represent a significant global health challenge and are often diagnosed at stages where curative options are not feasible. Transarterial therapies (TATs) have emerged as key locoregional treatment options for patients with unresectable liver tumors, using the liver's unique dual blood supply to selectively target tumor tissue while sparing healthy parenchyma. These therapies include transarterial embolization, transarterial chemoembolization, and transarterial radioembolization, each with distinct mechanisms, technical considerations, and clinical applications. This review provides a comprehensive overview of TATs, with focus on patient selection, procedural principles, and clinical effectiveness across primary and secondary liver malignancies.