Related Experiment Video
Updated: Aug 28, 2026

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy
Published on: May 22, 2020
Dermoids and dermal sinus tracts of the spine
Abstract:
The evaluation of a child with a midline dimple or pit is one of the most common referrals to a pediatric neurosurgeon. Regardless of their depth, those below the top of the intergluteal crease end blindly and never extend intraspinally. Families can be reassured there is no infection or mechanical risk to the developing nervous system. A high index of suspicion must be maintained for all dimples above the intergluteal fold despite a normal examination or neuroradiologic studies. The midline must be carefully inspected when a child of any age suffers meningitis, especially when an unusual organism is cultured. Conservative management of dermal sinuses is not justified, and these lesions should be electively resected at the time of diagnosis. Dermal sinuses and inclusion tumors may lead to spinal cord tethering and progressive neurologic deterioration. Surgery in advance of deficits maintains normal neurologic function, and children can develop unencumbered by infection, motor, or bladder paralysis.
Related Concept Videos
The Spinal Cord
Spinal Nerves: Anatomy
There are 31 bilateral pairs of spinal nerves, each emerging from the spinal cord through the intervertebral foramina—openings between adjacent vertebrae. These nerves are...
Cranial and Spinal Meninges
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
Veins of Head and Neck
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
Herniated Intervertebral Disc l: Introduction
Degenerative Disc Disease I: Introduction

