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[Prostatic malacoplakia: a case report]

H Takatera1, Y Yasunaga, H Kuroda

  • 1Department of Urology, Osaka Police Hospital.

Hinyokika Kiyo. Acta Urologica Japonica
|December 1, 1993
PubMed
Summary
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This case study highlights prostatic malacoplakia, a rare condition mimicking prostate cancer. Early diagnosis through biopsy is crucial for appropriate treatment of this uncommon urinary tract infection complication.

Area of Science:

  • Urology
  • Pathology
  • Microbiology

Background:

  • Prostatic malacoplakia is an uncommon inflammatory condition.
  • It can present with symptoms mimicking other prostatic diseases, including malignancy.
  • Urinary tract infections are often associated with malacoplakia.

Observation:

  • A 68-year-old man presented with fever, urinary retention, and a decreased urinary stream.
  • Urinalysis revealed Escherichia coli and Enterococcus faecalis.
  • Digital rectal examination and transrectal ultrasound suggested prostate cancer.

Findings:

  • Transrectal needle biopsy confirmed the histopathological diagnosis of prostatic malacoplakia.
  • The patient received a 5-month treatment regimen including trimethoprim-sulfamethoxazole, bethanechol, and ascorbic acid.

Related Experiment Videos

  • A review of 27 Japanese literature cases of prostatic malacoplakia was conducted.
  • Implications:

    • This case underscores the importance of histopathological examination for accurate diagnosis of prostatic malacoplakia.
    • Distinguishing malacoplakia from prostate cancer is vital for appropriate patient management.
    • Further research into the pathogenesis and optimal treatment of prostatic malacoplakia is warranted.