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Updated: Aug 9, 2026
09:23
Surgical Technique for Spinal Cord Delivery of Therapies: Demonstration of Procedure in Gottingen Minipigs
Published on: December 7, 2012
[Spinal cord sarcoidosis: diagnostic and therapeutic problems]
F Sebastián de la Cruz1, F La Banda Brusi, J Romero Ganuza
1Sección de Neurología, Hospital Nacional de Parapléjicos, Toledo.
Anales De Medicina Interna (Madrid, Spain : 1984)
|July 1, 1997
Summary
Spinal sarcoidosis is rare and challenging to diagnose, often mistaken for other conditions. Early MRI with gadolinium and prolonged prednisone treatment are crucial for managing spinal cord sarcoidosis.
Area of Science:
- Neurology
- Immunology
- Radiology
Background:
- Spinal cord sarcoidosis is an uncommon manifestation of systemic sarcoidosis.
- Diagnostic challenges include differentiating it from conditions like tuberculosis and paraneoplastic myelopathy.
Observation:
- Three cases of spinal cord sarcoidosis are presented, highlighting diagnostic difficulties.
- Initial MRI without contrast was unrevealing, but gadolinium-enhanced MRI revealed lesions in two patients.
Findings:
- Two patients experienced symptom improvement with prednisone, but relapsed upon dose reduction.
- Misdiagnosis led to incorrect initial treatments in all reported cases.
Implications:
- Spinal sarcoidosis diagnosis requires high clinical suspicion, especially in subacute or chronic myelopathies.
- Gadolinium-enhanced MRI is essential for detecting spinal cord lesions in suspected cases.
- Prolonged corticosteroid therapy, such as with prednisone, is recommended for managing spinal sarcoidosis.
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