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Estimation of deformation gradient and strain from cine-PC velocity data
1Department of Electrical Engineering, Stanford University, CA 94305, USA. yudong@s-word.stanford.edu
IEEE Transactions on Medical Imaging
|April 9, 1998
Summary
This study introduces a new method for quantifying myocardial strain using phase contrast MRI. The technique shows promise for noninvasive cardiac function analysis, though 3D data acquisition remains a challenge.
Area of Science:
- Cardiovascular Imaging
- Biomedical Engineering
- Medical Physics
Background:
- Phase contrast magnetic resonance imaging (MRI) enables in vivo myocardial velocity field measurements.
- Tracking material points throughout the cardiac cycle is crucial for deformation and strain quantification.
Purpose of the Study:
- To develop and validate a novel method for myocardial deformation and strain quantification using MRI-derived velocity data.
- To assess the accuracy and precision of the proposed method for cardiac function analysis.
Main Methods:
- Utilized Fourier tracking algorithm to track material points from velocity field data.
- Developed a method based on fitting tracking results to local deformation models.
- Validated the approach through computer simulations and phantom studies.
Main Results:
- The developed method demonstrated good agreement with expectations in simulations and phantom studies.
- Encouraging results were obtained from human heart data analysis.
- Predicted accuracy and precision suggest potential for clinical application at relevant SNR and resolution.
Conclusions:
- The proposed method offers a potentially powerful noninvasive approach for studying cardiac function.
- Further development is needed for clinically acceptable 3D data acquisition strategies.
- The technique shows promise for accurate myocardial strain quantification in clinical settings.