Philip G Humphreys
13PUBLICATIONS
29CO-AUTHORS
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Publications (13)
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|Jun 12, 2024
Structure- and Property-Based Optimization of Efficient Pan-Bromodomain and Extra Terminal Inhibitors to Identify Oral and Intravenous Candidate I-BET787.David J Hirst, Paul Bamborough, Niam Al-Mahdi
|Nov 15, 2023
Structure-Guided Design of a Domain-Selective Bromodomain and Extra Terminal N-Terminal Bromodomain Chemical Probe.Erin Bradley, Lucia Fusani, Chun-Wa Chung
|Nov 15, 2022
Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432.Philip G Humphreys, Niall A Anderson, Paul Bamborough
|Jan 07, 2022
Design, Synthesis, and Characterization of I-BET567, a Pan-Bromodomain and Extra Terminal (BET) Bromodomain Oral Candidate.Philip G Humphreys, Stephen J Atkinson, Paul Bamborough
|Aug 20, 2021
Optimization of Naphthyridones into Selective TATA-Binding Protein Associated Factor 1 (TAF1) Bromodomain Inhibitors.Michael A Clegg, Natalie H Theodoulou, Paul Bamborough
|Nov 18, 2020
Fragment-Based Identification of Ligands for Bromodomain-Containing Factor 3 of Trypanosoma cruzi.Corentine M C Laurin, Joseph P Bluck, Anthony K N Chan
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Frequent Collaborators
6 joint publications
Paul Bamborough
6 joint publications
Chun-Wa Chung
5 joint publications
Nicholas C O Tomkinson
4 joint publications
Christopher R Wellaway
3 joint publications
Rishi R Shah
2 joint publications
Gemma M Liwicki
2 joint publications
Katherine L Jones
1 joint publications
Zuni I Bassi
1 joint publications
Ian Churcher
1 joint publications
David J Hirst
