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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

343
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
343
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

316
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
316

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Related Experiment Video

Updated: Jun 14, 2025

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
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[Cancer in kidney transplant recipients].

Evelyne Smith1, Tobias Zingg1, Maurice Matter1

  • 1Service de chirurgie viscérale, Centre hospitalier universitaire vaudois, Université de Lausanne, 1011 Lausanne.

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Kidney transplant recipients face double the cancer risk due to immunosuppression and viruses. Early cancer screening for candidates and tailored post-transplant surveillance are crucial for managing this risk.

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Area of Science:

  • Oncology
  • Nephrology
  • Transplant Surgery

Context:

  • Kidney transplant recipients have a significantly higher cancer risk compared to the general population.
  • Cancer is the second leading cause of mortality in this patient group, following cardiovascular diseases.
  • The elevated risk is linked to factors including oncogenic viruses and the necessary immunosuppression post-transplant.

Purpose:

  • To highlight the increased cancer risk in kidney transplant recipients.
  • To outline recommended screening and management strategies for cancer in this population.
  • To emphasize the multifactorial nature of cancer development post-transplantation.

Summary:

  • Kidney transplant recipients are at least twice as likely to develop or die from cancer.
  • Screening for cancer is essential for transplant candidates and donors.
  • Post-transplant cancer management involves conventional treatments and adjusting immunosuppression.

Impact:

  • Informing clinical practice regarding cancer surveillance in kidney transplant patients.
  • Guiding the development of personalized cancer screening protocols.
  • Improving long-term outcomes for kidney transplant recipients by addressing cancer risks.