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Updated: May 24, 2025

A Procedure for Implanting Organized Arrays of Microwires for Single-unit Recordings in Awake, Behaving Animals
Published on: February 14, 2014
A Motion-Artifact-Tolerant Biopotential-Recording IC With a Digital-Assisted Loop
This study introduces a new integrated circuit (IC) for recording biopotential signals, featuring a digital-assisted loop (DAL) to effectively track motion artifacts. This robust IC ensures high-quality signal acquisition even in the presence of significant movement, improving biopotential monitoring.
Area of Science:
- Biomedical Engineering
- Integrated Circuit Design
- Signal Processing
Background:
- Motion artifacts are a significant challenge in multi-channel biopotential recording, often leading to signal loss and reduced data quality.
- Existing systems struggle to accurately track and compensate for large amplitude motion artifacts across varying bandwidths.
- Electrode DC offsets and 1/f noise further degrade the quality of recorded biopotential signals.
Purpose of the Study:
- To propose and characterize a novel motion-artifact-tolerant multi-channel biopotential-recording integrated circuit (IC).
- To demonstrate the effectiveness of a digital-assisted loop (DAL) in tracking and mitigating motion artifacts.
- To achieve low noise levels and high signal-to-noise-and-distortion ratio (SNDR) for reliable biopotential signal acquisition.
Main Methods:
- Implementation of a novel counter-based digital-assisted loop (DAL) for motion artifact tracking.
- Integration of four analog front-end (AFE) channels sharing a programmable gain amplifier (PGA) and analog-to-digital converter (ADC) via time-multiplexing.
- Inclusion of a chopper with an analog DC-servo loop (DSL) for electrode DC offset (EDO) cancellation and 1/f noise reduction.
Main Results:
- The DAL effectively tracks motion artifacts up to 120 mV with a 10 Hz bandwidth and up to 240 mV with a 5 Hz bandwidth without signal loss.
- The fabricated IC achieves a low input-referred noise (IRN) of 0.71 µV over a 0.5–500 Hz bandwidth and an SNDR of 63.34 dB.
- The IC demonstrates efficient power consumption (5.74 µW) and a compact area (0.40 mm²/channel) in a 0.18-µm CMOS process.
Conclusions:
- The proposed IC offers robust performance in the presence of significant motion artifacts, making it suitable for various biopotential recording applications.
- The combination of DAL, shared PGA/ADC, and DSL effectively addresses key challenges in biopotential signal acquisition, including motion artifacts, DC offsets, and noise.
- This artifact-tolerant, low-noise IC represents a significant advancement for wearable and implantable biopotential monitoring systems.
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